Thomas Arendt

Head of Paul Flechsig Institute of Brain Research
Neuroanatomy Department
Paul Flechsig Institute of Brain Research

Fields of interest:

Alzheimer’s disease – pathogenesis and therapy; analysing inflammatory processes related to neurodegeneration, especially in the cholinergic system; investigating the role of extracellular matrix during cell loss; involvement of glia in CNS function and pathology.


Recent publications:

Voigt C, Donat CK, Hartig W, Förschler A, Skardelly M, Stichtenoth D, Arendt T, Meixensberger J, Schuhmann MU.:
Effect of leukotriene inhibitors on evolution of experimental brain contusions.
Neuropathol Appl Neurobiol, 2011, 1365-2990

Tedde A, Piaceri I, Bagnoli S, Lucenteforte E, Ueberham U, Arendt T, Sorbi S, Nacmias B.:
Association Study of Genetic Variants in CDKN2A/CDKN2B Genes/Loci with Late-Onset Alzheimer’s Disease.
Int J Alzheimers Dis, 2011, 2011:374631

Salkovic-Petrisic M, Osmanovic-Barilar J, Brückner MK, Hoyer S, Arendt T, Riederer P.:
Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer’s disease: a long-term follow up study.
J Neural Transm,2011, 118:765-72

Reinert A, Mittag A, Reinert T, Tárnok A, Arendt T, Morawski M.:
On the quantification of intracellular proteins in multifluorescence-labeled rat brain slices using slide-based cytometry.
Cytometry A,2011, 79:485-91

Alpár A, Ueberham U, Lendvai D, Naumann N, Rohn S, Gáti G, Arendt T, Gärtner U.:
Activity-induced dendrite and dendritic spine development in human amyloid precursor protein transgenic mice.
Int J Dev Neurosci,2011, 29:107-14

Stieler JT, Bullmann T, Kohl F, Tøien Ø, Brückner MK, Härtig W, Barnes BM, Arendt T.:
The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation.
PLoS One, 2011, 6:e14530

Gáti G, Morawski M, Lendvai D, Jäger C, Négyessy L, Arendt T, Alpár A.:
Distribution and classification of aggrecan-based extracellular matrix in the thalamus of the rat.
J Neurosci Res, 2010, 88:3257-66

Bullmann T, Härtig W, Holzer M, Arendt T.
Expression of the embryonal isoform (0N/3R) of the microtubule-associated protein tau in the adult rat central nervous system.
J Comp Neurol, 2010, 518:2538-53

Arendt T, Brückner MK, Mosch B, Lösche A.:
Selective cell death of hyperploid neurons in Alzheimer’s disease.
Am J Pathol,2010, 177:15-20

Stieler J, Grimes R, Weber D, Gartner W, Sabbagh M, Arendt T.
Multivariate analysis of differential lymphocyte cell cycle activity in Alzheimer’s disease.
Neurobiol Aging,2010, Apr 13.