Fields of interest:
Insect immunity; host-pathogen interactions; microRNAs; Insect virology
Ma G, Rahman MM, Grant W, Schmidt O, Asgari S:
Insect tolerance to the crystal toxins Cry1Ac and Cry2Ab is mediated by the binding of monomeric toxin to lipophorin glycolipids causing oligomerization and sequestration reactions.
Developmental & Comparative Immunology, (2012) In press.
Hussain M, Torres S, Schnettler E, Funk A, Grundhoff A, Pijlman GP, Khromykh AA, Asgari S:
West Nile virus encodes a microRNA-like small RNA in the 3’ untranslated region which upregulates GATA4 mRNA and facilitates virus replication in mosquito cells.
Nucleic Acids Research, 40, (2012): 2210-2223.
Etebari K, Palfreyman R, Schlipalius D, Nielsen L, Glatz RV, Asgari S:
Deep sequencing-based transcriptome analysis of Plutella xylostella larvae parasitized by Diadegma semiclausum.
BMC Genomics, 12, (2011): 446.
Role of microRNAs in insect host-microorganism interactions.
Frontiers in Physiology (Invertebrate Physiology), 2, (2011): 48.
Hussain M, Frentiu FD, Moreira LA, O’Neill SL, Asgari S:
Wolbachia utilizes host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti.
Proceedings of the National Academy of Sciences USA, 108, (2011): 9250–9255.
Cooper TH, Bailey-Hill K, Leifert WR, McMurchie EJ, Asgari S, Glatz R:
Identification of an in vitro interaction between an insect immune-suppressor protein (CrV2) and G proteins.
Journal of Biological Chemistry, 286, (2011): 10466-10475.
Thomas P, Kenny N, Eyles D, Moreira LA, O’Neill SL, Asgari S:
Infection with the wMel and wMelPop strains of Wolbachia leads to higher levels of melanization in the hemolymph of Drosophila melanogaster, Drosophila simulans and Aedes aegypti.
Developmental & Comparative Immunology, 35, (2011): 360–365.
Asgari S, Rivers DB:
(2011) Venom proteins from endoparasitoid wasps and their role in host-parasite interactions. Annual Review of Entomology 56, 313-335.
Hussain M, Asgari S:
Functional analysis of a cellular microRNA in insect host-ascovirus interaction.
Journal of Virology, 84, (2010): 612-620.
Hussain M, Taft RJ, Asgari S:
An insect virus-encoded microRNA regulates viral replication.
Journal of Virology, 82, (2008): 9164-9170.