Federico Bolognani

Head Safety Genomics
Division of Translational Neurosciences
Novartis Institute for Biomedical Research, Basel Area, Switzerland
E-mail: fbolognani@gmail.com
Page: http://www.bolognani.org/

Fields of interest

Toxicology, neuro-oncology, RNA biology, experimental medicine, translational research, gene expression, data mining.


Recent publications

Herzig MC, Kolly C, Persohn E, Theil D, Schweizer T, Hafner T, Stemmelen C, Troxler TJ, Schmid P, Danner S, Schnell CR, Mueller M, Kinzel B, Grevot A, Bolognani F, Stirn M, Kuhn RR, Kaupmann K, van der Putten PH, Rovelli G, Shimshek DR.:
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.
Hum Mol Genet., 2011, 20(21):4209-23

Jagannathan K, Calhoun VD, Gelernter J, Stevens MC, Liu J, Bolognani F, Windemuth A, Ruaño G, Assaf M, Pearlson GD.:
Genetic associations of brain structural networks in schizophrenia: a preliminary study.
Biol Psychiatry., 2010, 1;68(7):657-66

Bolognani F, Contente-Cuomo T, Perrone-Bizzozero NI.:
Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets.
Nucleic Acids Res., 2010, 38(1):117-30

Bullock WM, Bolognani F, Botta P, Valenzuela CF, Perrone-Bizzozero NI.:
Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine.
Neurochem Int., 2009, 55(8):775-82

Tanner DC, Qiu S, Bolognani F, Partridge LD, Weeber EJ, Perrone-Bizzozero NI.:
Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD.
Hippocampus.,2008, 18(8):814-23

Bolognani F, Tanner DC, Nixon S, Okano HJ, Okano H, Perrone-Bizzozero NI.:
Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity.
Neurochem Res., 2007, 32(12):2142-51

Deschênes-Furry J, Mousavi K, Bolognani F, Neve RL, Parks RJ, Perrone-Bizzozero NI, Jasmin BJ.:
The RNA-binding protein HuD binds acetylcholinesterase mRNA in neurons and regulates its expression after axotomy.
J Neurosci., 2007, 27(3):665-75

Bolognani F, Qiu S, Tanner DC, Paik J, Perrone-Bizzozero NI, Weeber EJ.:
Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD.
Neurobiol Learn Mem., 2007, 87(4):635-43

Bizzozero OA, Ziegler JL, De Jesus G, Bolognani F.:
Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins.
J Neurosci Res., 2006, 83(4):656-67

Bolognani F, Tanner DC, Merhege M, Deschênes-Furry J, Jasmin B, Perrone-Bizzozero NI.:
In vivo post-transcriptional regulation of GAP-43 mRNA by overexpression of the RNA-binding protein HuD.
J Neurochem., 2006, 96(3):790-801