Carlos Fernández-Hernando

Assistant Professor of Medicine and Cell Biology
Medicine and Cell Biology
New York University School of Medicine
E-mail: Carlos.fernandez-hernando@nyumc.org
Page: http://www.med.nyu.edu/biosketch/fernac08

Fields of interest

Cholesterol metabolism,
Cardiovascular disease,
Atherosclerosis and angiogenesis 

 

Recent publications

Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ and Sessa WC.
Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease.
Cell Metab., 6: 446-457 (2007)

Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M and Sessa WC.
Dicer-dependent endothelial microRNAs are necessary for post-natal angiogenesis.
Proc Natl Acad Sci USA., 105: 14082-14087 (2008)

Fernández-Hernando C, Yu J, Suárez Y, Rahner C, Dávalos A, Lasunción MA and Sessa WC.
Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis.
Cell Metab., 10: 48-54 (2009)

Harrison KD, Miao RQ, Fernández-Hernando C, Suárez Y, Dávalos A and Sessa WC.
Nogo-B receptor stabilizes Niemann-Pick Type C2 protein and regulates intracellular cholesterol trafficking.
Cell Metab., 10(3): 208-18 (2009)

Rayner KJ, Suárez Y, Dávalos A, Parathath S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ and Fernández-Hernando
mir-33 coordinates genes regulating cholesterol homeostasis.
C. Science., 328 (5985): 1570-3 (2010)

Dávalos A, Goedeke L, Smibert P, Warrier N.P, Andreo U, Rayner K, Suresh U, Pastor-Pareja JC, Fisher EA, Penalva LF, Moore KJ, Suárez Y, Lai EC, Fernández-Hernando C.
miR-33a/b coordinates genes regulating fatty acid metabolism and insulin signaling.
Proc Natl Acad Sci. USA., 108(22):9232-7 (2011)

Rayner KJ, Sheedy FJ, Esau CC, Hussain FN, Temel RE, Parathath S, Rayner AJ, Chang A, Suárez Y, Fernández-Hernando C, Fisher EA and Moore KJ.
Antagonist of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis.
J Clin Invest., 121(7):2921-31 (2011)

Rayner K, Essau CC, Hussain FN, McDaniel AL, Marshall SM, Van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernández-Hernando C, Fisher EA, Temel RE and Moore KJ.
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
Nature, 478(7369):404-7 (2011)

Dávalos A, Ramírez CM, Goedeke L, Salerno AG, Warrier N, Suárez Y andFernández-Hernando C.
miR-758 regulates cholesterol efflux through post-transcriptional repression of ABCA1 Arterioscler.
Thromb. Vasc. Biol
., 31(11):2707-14 (2011)

Cirera-Salinas D, Pauta M, Allen RM, Salerno AG, Ramírez CM,Wanschel AC, Lasunción MA, Morales-Ruiz M, Suárez Y, Baldán A, EspluguesEandFernández-Hernando C.
mir-33 regulates cell proliferation and cell cycle progression.
Cell Cycle., 11(5):922-33 (2012)