V. Peter Collins

Professor
Department of Pathology
University of Cambridge
E-mail: vpc20@cam.ac.uk
Page: http://www.path.cam.ac.uk/research/investigators/collins-ichimura/

Fields of interest: 

Histopathology, Neuropathology, Brain Tumours, Molecular Genetics

 

Recent publications:

Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturn D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jäger N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Frühwald MC, Roggendorf W, Kramm C, Dürken M, Atkinson J, Lepage P, Montpetit A, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel P, Kulozik AE, Zapatka M, Guha A, Malkin D, Felsberg J, Reifenberger G, von Deimling A, Ichimura K, Collins VP, Witt H, Milde T, Witt O, Zhang C, Castelo-Branco P, Lichter P, Faury D, Tabori U, Plass C, Majewski J, Pfister SM, Jabado N.:
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
Nature, 2012, 482(7384), 226-231.

Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, Majewski J, Scheetz TE, Pfister SM, Korshunov A, Li XN, Scherer SW, Cho YJ, Akagi K, Macdonald TJ, Koster J, McCabe MG, Sarver AL, Collins VP, Weiss WA, Largaespada DA, Collier LS, Taylor MD.:
Clonal selection drives genetic divergence of metastatic medulloblastoma. 
Nature2012, 482(7386):529-33

Jacob K, Quang-Khuong DA, Jones DT, Witt H, Lambert S, Albrecht S, Witt O, Vezina C, Shirinian M, Faury D, Garami M, Hauser P, Klekner A, Bognar L, Farmer JP, Montes JL, Atkinson J, Hawkins C, Korshunov A, Collins VP, Pfister SM, Tabori U, Jabado N.:
Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas.
Clin Cancer Res. 2011, 17(14):4650-60

Ichimura, K., Pearson, D.M., Kocialkowski, S., Backlund, L.M., Chan, R., Jones, D.T., and Collins, V.P.:
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas.
Neuro Oncol  2009, 11, 341-347.

Jones, D.T., Kocialkowski, S., Liu, L., Pearson, D.M., Ichimura, K., and Collins, V.P.:
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.
Oncogene2009, 28, 2119-2123.