Laurence Coutellier

Assistant Professor
Departments of Psychology and Neuroscience (Courtesy)
The Ohio State University, OH, USA

Fields of interest

Behavioral neuroscience, neurodegenerative diseases.

Recent publications


Ardestani PM, Evans AK, Yi B, Nguyen T, Coutellier L, Shamloo M. (In press) Modulation of
neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer’s Disease using a biased and selective beta-1 adrenergic receptor partial agonist. Neuropharmacology.

Shepard R, Heslin K, Coutellier L. (2016) The transcription factor Npas4 contributes to adolescent development of prefrontal inhibitory circuits, and to cognitive and emotional functions: implications for neuropsychiatric disorders. Neurobiology of Disease. 99:36-46

Shepard R, Page CE, Coutellier L. (2016) Sensitivity of the prefrontal GABAergic system to chronic stress in male and female mice: relevance for sex differences in stress-related disorders. Neuroscience. 332:1-12.

Coutellier L.*, Gilbert V., Shepard R. (2015) Npas4 deficiency increases vulnerability to juvenile stress in mice. Behavioural Brain Research. 295:17-25. *senior author

Coutellier L., Ardestani PM., Shamloo M. (2014) β1-adrenergic receptor activation enhances memory in Alzheimer’s disease model. Annals of Clinical and Translational Neurology. 1(5): 348-360.

Stephan AH, Madison DV, Mateos JM, Fraser DA, Lovelett EA, Coutellier L, Kim L, Tsai HH, Huang EJ, Rowitch DH, Berns DS, Tenner AJ, Shamloo M, Barres BA. (2013) A dramatic increase of C1q protein in the CNS during normal aging. Journal of Neuroscience 33(33):13460-74

Coutellier L., Beraki S., Ardestani P.M., Saw N.L., Shamloo M. (2012) Npas4: a neuronal transcription factor with a key role in social and cognitive functions relevant for developmental disorders. Plos One. 7(9):e46604

Coutellier L. (2012) Rodent models of early environment effects on offspring development and
susceptibility to neurological diseases in adulthood. Translational Neuroscience. 3 (3): 258-262.
Coutellier L., Logemann A., Rusnak, M and Usdin T. (2011) Maternal absence of the parathyroidhormone 2 (PTH2) receptor affects postnatal pup development. Journal of Neuroendocrinology. 23(7): 612-619.

Coutellier L. and Usdin T. (2011) Enhanced long-term fear memory and increased anxiety and
depression-like behavior after exposure to an aversive event in mice lacking TIP39 signaling.
Behavioural Brain Research. 222(1): 265-269.

Coutellier L., Logemann A. Kuo, J., Rusnak, M. and Usdin T. (2011) TIP39 modulates effects of noveltyinduced arousal on memory. Genes, Brain and Behavior, 10 (1): 90-99.

Coutellier L. and Würbel H. (2009) Early environmental cues affect object recognition memory in
adult female but not male C57BL/6 mice. Behavioral Brain Research. 203: 312-315.

Coutellier L., Friedrich, A.C., Failing, K., Marashi, V. and Würbel, H. (2009) Effects of variations in
foraging demand on maternal behaviour and adult offspring anxiety and stress response in C57BL/6 mice. Behavioral Brain Research. 196 (2): 192-199.

Coutellier L., Friedrich, A.C., Failing, K., Marashi, V. and Würbel, H. (2008) Effects of rat odour and
shelter on maternal behaviour in C57BL/6 dams and on fear and stress responses in their adult
offspring. Physiology and Behavior, 94: 393-404.

Coutellier L., Friedrich, A.C., Failing, K. and Würbel, H. (2008) Variation of postnatal maternal
environment in mice: effects on maternal behaviour and behavioural and endocrine responses in the adult offspring. Physiology and Behavior, 93: 395-407.

Coutellier L., C. Arnould, A. Boissy, P. Orgeur, A. Prunier, I. Veissier, M.C. Meunier-Salaün (2007) Pig’s responses to repeated social regrouping and relocation during the growing-finishing period. Applied Animal Behaviour Science, 105:102-114.

Coutellier L. (2006) Are dogs able to recognize their handler’s voice? A preliminary study. Anthrozöos, 19(3): 278-284.

Coutellier L. (2006) Working dogs (Canis familiaris) use human vocal and gestural cues to respond to verbal commands. Ethologie 12: 9-16. Article in French.


Coutellier L. (2013) Adaptive regulations in developing rodents following neonatal challenges. In G. Laviola and S. Macri. (Eds) (Mal)adaptive aspects of developmental stress. Springer Neurotoxicity Book Series.