Joseph Coyle

Eben S. Draper Professor of Psychiatry
Department of Psychiatry
McLean Hospital
E-mail: joseph_coyle@hms.harvard.edu
Page: http://hms.harvard.edu/WhitePagesPublic.asp?task=showperson&id=HVQ0aWJEODc=&a=hms&r=2&kw=

Fields of interest

Developmental neurobiology, mechanisms of neuronal vulnerability, psychopharmacology, role of glutamatergic neurons in the pathophysiology of neuropsychiatric disorders.

 

Recent publications

Balu DT, Coyle JT.:
Glutamate receptor composition of the post-synaptic density is altered in genetic mouse models of NMDA receptor hypo- and hyperfunction.
Brain Res., 2011, 1392:1-7

Benneyworth MA, Roseman AS, Basu AC, Coyle JT.:
Failure of NMDA receptor hypofunction to induce a pathological reduction in PV-positive GABAergic cell markers.
Neurosci Lett., 2011, 488(3):267-71

Devito LM, Balu DT, Kanter BR, Lykken C, Basu AC, Coyle JT, Eichenbaum H.:
Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology.
Genes Brain Behav., 2011, 10(2):210-22

Balu DT, Coyle JT.:
Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia.
Neurosci Biobehav Rev., 2011, 35(3):848-70

Benneyworth MA, Basu AC, Coyle JT.:
Discordant behavioral effects of psychotomimetic drugs in mice with altered NMDA receptor function.
Psychopharmacology (Berl)., 2011, 213(1):143-53

Mustafa AK, Ahmad AS, Zeynalov E, Gazi SK, Sikka G, Ehmsen JT, Barrow RK, Coyle JT, Snyder SH, Doré S.:
Serine racemase deletion protects against cerebral ischemia and excitotoxicity.
J Neurosci., 2010, 30(4):1413-6

Coyle JT, Balu D, Benneyworth M, Basu A, Roseman A.:
Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.
Dialogues Clin Neurosci., 2010, 12(3):359-82

Reed BT, Sullivan SJ, Tsai G, Coyle JT, Esguerra M, Miller RF.:
The glycine transporter GlyT1 controls N-methyl-D-aspartic acid receptor coagonist occupancy in the mouse retina.
Eur J Neurosci., 2009, 30(12):2308-17

Han L, Picker JD, Schaevitz LR, Tsai G, Feng J, Jiang Z, Chu HC, Basu AC, Berger-Sweeney J, Coyle JT.:
Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II.
Synapse., 2009, 63(8):625-35

Ghose S, Chin R, Gallegos A, Roberts R, Coyle J, Tamminga C.:
Localization of NAAG-related gene expression deficits to the anterior hippocampus in schizophrenia.
Schizophr Res., 2009, 111(1-3):131-7