Fields of interest:
Biocatalysis, Cascade reactions, Enzyme technology, Carbohydrate bioengineering,
Eduardo García-Junceda studied Biology at the Universidad Complutense (Madrid, Spain). He completed his doctoral studies in 1990 under the supervision of Prof. Dr. Carlos Vicente at the Plant Physiology Department of the Faculty of Biology (UCM). After earning his Ph.D., he served as a postdoctoral fellow at CSIC, first in the Department of Instrumental Analysis and Enviromental Chemistry of the Institute of Organic Chemistry (IQOG) and later in the Department of Biocatalysis of the Institute of Catalysis and Petrochemistry (ICP). In 1992, Dr. García-Junceda joined the Group of Dr. Chi-Huey Wong at The Scripps Research Institute (La Jolla, California) as postdoctoral fellow, where he began to work on the obtaining and use of enzymes for carbohydrate synthesis. After his return to Spain in 1995, he was appointed Research Staff Member at IQOG of CSIC in 1997 and in 2009 he was promoted to Associate Research Member in the same Institute.
Besides being author of more than 50 scientific publications and Patents, Dr. García-Junceda has been editor of the book Multi-Step Enzyme Catalysis: Biotransformations and chemoenzymatic Synthesis (2008, Wiley-VCH Verlag GMBH & Co. KGaA. Weinheim, Alemania) and has supervised five PhD Theses.
Some of the research topics that are currently being developed in the laboratory of Dr. García-Junceda are:
Design and development of new multienzyme systems and multifunctional enzymes for the synthesis of carbohydrates with special emphasis on C-C bond formation catalyzed by DHAP dependent aldolases and regioselective sulfation of oligosaccharides
Chemo-enzymatic synthesis of biocompatible materials functionalized with analogs of heparan and chondroitin sulfate for regeneration of the central nervous system (CNS).
Using techniques of Enzyme Directed Evolution and protein engineering to obtain biocatalysts with new activities and properties