Eric Miska

Group Leader
Gurdon Institute
University of Cambridge
E-mail: eric.miska@gurdon.cam.ac.uk
Page: http://www.gurdon.cam.ac.uk/~miskalab/

Fields of interest

Genetic,
Genomics,
small RNA biology,
C. elegans

 

Recent publications

Jovanovic M., Reiter L., Picotti P., Lange V., Bogan E., Hurschler B. A., Blenkiron C., Lehrbach N. J., Ding X. C., Weiss M., Schrimpf S. P., Miska E. A., Grosshans H., Aebersold R., Hengartner M. O.
A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans. 
Nat. Methods, 7: 837–842 (2010)

Baudet M.-L., Zivraj K. H., Abreu-Goodger C., Muldal A., Armisen J., Blenkiron C., Goldstein L. D., Miska E. A., Holt C. E.
miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones.
Nat. Neurosci., 15: 29–38 (2011)

Félix M.-A., Ashe A., Piffaretti J., Wu G., Nuez I., Bélicard T., Jiang Y., Zhao G., Franz C. J., Goldstein L. D., Sanroman M., Miska E. A.*, Wang D.
Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses. 
PLoS Biol., 9: e1000586 (2011)

Lightfoot H. L., Bugaut A., Armisen J., Lehrbach N. J., Miska E. A.*, Balasubramanian S.
A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. 
Biochemistry, 50: 7514–7521 (2011)

Kamminga L. M., van Wolfswinkel J. C., Luteijn M. J., Kaaij L. J. T., Bagijn M. P., Sapetschnig A., Miska E. A., Berezikov E., Ketting R. F.
Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of Caenorhabditis elegans.
PLoS Genet., 8: e1002702 (2012)

Ashe A., Sapetschnig A., Weick E.M., Mitchell J., Bagijn M.P., Cording A., Doebley A.L., Goldstein L.D., Lehrbach N.J., Le Pen J., Pintacuda G., Sakaguchi A., Sarkies P., Ahmed S., Miska E. A.
piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans.
Cell, 150: 88–99 (2012)

Bagijn M. P., Goldstein L. D., Sapetschnig A., Weick E.-M., Bouasker S., Lehrbach N. J., Simard M. J., Miska E. A.
Function, Targets, and Evolution of Caenorhabditis elegans. 
piRNAs Science, published online 14 June 2012.

Jovanovic M., Reiter L., Clark A., Weiss M., Picotti P., Rehrauer H., Frei A., Neukomm L. J., Kaufman E., Wollscheid B., Simard M. J., Miska E. A., Aebersold R., Gerber A. P., Hengartner M. O.
RIP-chip-SRM–a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans.
Genome Res., doi:10.1101/gr.133330.111 (2012)

Vasquez-Rifo A., Jannot G., Armisen J., Labouesse M., Bukhari S. I. A., Rondeau E. L., Miska E. A., Simard M. J.
Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2 .
PLoS One, 7: e33750 (2012)

Castro C., Sar F., Shaw W. R., Mishima M., Miska E. A., Griffin J. L.
A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans. 
BMC Genomics, 13: 36 (2012)