Isidro Ferrer

Professor of Pathology, Neuropathology; Director Institute of Neuropathology
Department of Pathology and Experimental Therapeutics, Institute of Neuropathology
niversity of Barcelona; IDIBELL-Hospital Universitari de Bellvitge; CIBERNED

Fields of Interest

  • Clinical and experimental neuropathology, neurodegenerative disorders, cerebrovascular diseases
  • Early molecular changes in neurodegenerative diseases with abnormal protein aggregates

Recent publications

Ferrer I, Santpere G, Arzberger T, Bell J, Blanco R, Boluda S, Budka H, Carmona M, Giaccone G, Krebs B, Limido L, Parchi P, Puig B, Strammiello R, Strobel T, Kretzschmar H:
Brain protein preservation largely depends on the postmortem storage temperature: implications for study of proteins in human neurologic diseases and management of brain banks: a BrainNet Europe Study,
J. Neuropathol. Exp. Neurol., 2007, 66, 35-46

Dalfo E, Ferrer I:
Early-alpha-synuclein lipoxidation in neocortex in Lewy body diseases,
Neurobiol. Aging, 2008, 29, 408-417

Ferrer I, Santpere G van Leeuwen FW:
Argyrophilic grain disease,
Brain, 2008, 131, 1416-1432

Martinez A, Carmona M, Portero-Otin M, Naudi A, Pamplona R, Ferrer I:
Type-dependent oxidative damage in frontotemporal lobar degeneration: cortical astrocytes are targets of oxidative damage.
J. Neuropathol. Exp. Neurol., 2008, 67, 1122-1136

Santpere G, Ferrer I:
Delineation of early changes in cases with progressive supranuclear palsy-like pathology. Astrocytes in striatum are primary targets of tau phosphorylation and GFAP oxidation,
Brain Pathol., 2009, 19, 177-187

Navarro A, Boveris A, Bández MJ, Sanchez-Pinto MJ, Gómez C, Muntane G, Ferrer I:
Human brain cortex: mitochondrial oxidative damage and adaptative response in Parkinson disease and dementia with Lewy bodies,
Free Radic. Biol. Med., 2009, 46, 1574-1580

Ferrer I:
Early involvement of the cerebral cortex in Parkinson’s disease: Convergence of multiple metabolic defects,
Prog. Neurobiol., 2009, 88, 89-103

Ferrer I, Santpere G, Puig B:
Immediate early genes, inducible transcription factors and stress kinases in Alzheimer’s disease.
In: Immediate early genes in sensory processing, cognitive performance and neurological disorders, Pinaud R, Tremere LA (eds), Springer, New York, 2006, 243-260

Ferrer I, Kaste M, Kalimo H:
Vascular diseases.
In: Greenfield’s Neuropathology. Eighth edition. Love S, Louis DN, Ellison DW (eds) Hodder Arnold, London, 2008, 121-240

Muñoz DG, Ferrer I:
Neuropathology of hereditary forms of frontotemporal dementia and parkinsonism.
In: Handbook of Clinical Neurology, vol 89: Dementias. Duyckaerts C, Litvan I (eds) Elsevier, Edinburgh, London, New York, Oxford, Philadelphia, St Louis, Sydney, Toronto, 2008, 393-414