Fabio Martelli

Molecular Cardiology Laboratory, Director
IRCCS-Policlinico San Donato, Milan, Italy
E-mail: fabio.martelli@grupposandonato.it

Fields of interest

Investigating microRNA regulation and role in the molecular mechanisms underpinning tissue response to hypoxia and ischemia. Particular attention is devoted to complicating factors such as diabetes mellitus.

 

Recent publications

 

Greco S, Perfetti A, Fasanaro P, Cardani R, Capogrossi MC, Meola G, Martelli F.
Deregulated microRNAs in myotonic dystrophy type 2.
PLoS One,  7(6):e39732 (2012)

Greco S, Fasanaro P, Castelvecchio S, D’Alessandra Y, Arcelli D, Di Donato M, Malavazos A, Capogrossi MC, Menicanti L, Martelli F.
MicroRNA dysregulation indiabetic ischemic heart failure patients.
Diabetes,  61(6):1633-41 (2012)

Voellenkle C, Rooij Jv, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L, David M, Capogrossi MC, Moles A, Felsani A, Martelli F.
Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs.
RNA, 18(3):472-84 (2012)

Perbellini R, Greco S, Sarra-Ferraris G, Cardani R, Capogrossi MC, Meola G, Martelli F.
Dysregulation and cellular mislocalization of specific miRNAs in myotonic dystrophy type 1.
Neuromuscul Disord., 21(2):81-8 (2011)

Hu S, Huang M, Li Z, Jia F, Ghosh Z, Lijkwan MA, Fasanaro P, Sun N, Wang X, Martelli F, Robbins RC, Wu JC.
MicroRNA-210 as a novel therapy for treatment of ischemic heart disease.
Circulation,122(11 Suppl):S124-31 (2010)

D’Alessandra Y, Devanna P, Limana F, Straino S, Di Carlo A, Brambilla PG, Rubino M, Carena MC, Spazzafumo L, De Simone M, Micheli B, Biglioli P, Achilli F, Martelli F, Maggiolini S, Marenzi G, Pompilio G, Capogrossi MC.
Circulating microRNAs are new and sensitive biomarkers of myocardial infarction.
Eur Heart J., 31(22):2765-73 (2010)

Voellenkle C, van Rooij J, Cappuzzello C, Greco S, Arcelli D, Di Vito L, Melillo G, Rigolini R, Costa E, Crea F, Capogrossi MC, Napolitano M, Martelli F.
MicroRNA signatures in peripheral blood mononuclear cells of chronic heart failure patients.
Physiol Genomics, 42(3):420-6 (2010)

Fasanaro P, Greco S, Lorenzi M, Pescatori M, Brioschi M, Kulshreshtha R, Banfi C, Stubbs A, Calin GA, Ivan M, Capogrossi MC, Martelli F.
An integrated approach for experimental target identification of hypoxia-induced miR-210.
J Biol Chem., 284(50):35134-43 (2009)

Greco S, De Simone M, Colussi C, Zaccagnini G, Fasanaro P, Pescatori M, Cardani R, Perbellini R, Isaia E, Sale P, Meola G, Capogrossi MC, Gaetano C, Martelli F.
Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia.
FASEB J., 23(10):3335-46 (2009)

Fasanaro P, D’Alessandra Y, Di Stefano V, Melchionna R, Romani S, Pompilio G, Capogrossi MC, Martelli F.
MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3.
J Biol Chem., 283(23):15878-83 (2008)