Elizabeth Head

Associate Professor
Sanders-Brown Center on Aging
University of Kentucky
E-mail: elizabeth.head@uky.edu

Fields of interest

  • Neurodegenerative disease and brain aging
  • Animal models of aging and Alzheimer's disease (dog) and aging in Down syndrome


Recent publications

Head E., V. Pop, V. Vasilevko, M. Hill, T. Saing, F. Sarsoza, M. Nistor, L.A. Christie, S. Milton, C. Glabe, E. Barrett, D. Cribbs:
A 2-Year Study with Fibrillar A Immunization in Aged Canines: Effects on Cognitive Function and Brain A.
Journal of Neuroscience, 2008, 28: 3555-3566

Head E., V.N. Nukala, K.A. Fenoglio, B.A. Muggenburg, C.W. Cotman, and P.G. Sullivan:
Effects of age, dietary and behavioral enrichment on brain mitochondria in a canine model of human aging.
Experimental Neurology, 2009, 220(1): 171-176

Cotman C.W. and E. Head:
The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches.
J. Alzheimers Dis., 2008, 15(4): 685-707

Head E., I.T. Lott, D. Patterson, E. Doran, R.J. Haier:
Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology.
Journal of Alzheimer’s Disease, 2007, 11(1):61-76

Sarsoza F., T. Saing, R. Kayed, R. Dahlin, M. Dick, C. Broadwater-Hollifield, S. Mobley, I. Lott, E. Doran, D. Gillen, C. Anderson-Bergman, D. H. Cribbs, C. Glabe, E. Head:
A fibril specific, conformation dependent antibody recognizes a subset of Aβ plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain.
Acta Neuropathologica, 2009, 118 (4) 505

Head E., M.M. Corrada, K. Kahle-Wrobleski, R.C. Kim, F. Sarsoza, M. Goodus, C.H. Kawas:
Synaptic proteins, neuropathology and cognitive status in the oldest-old.
Neurobiology of Aging, 2009, 30(7): 1125-1134