Holger Stark

PortraithochST

Professor
Institute of Pharmaceutical and Medicinal Chemistry
Heinrich Heine University Duesseldorf
E-mail: stark@hhu.de
Page: http://www.pharmazie.uni-duesseldorf.de/Institute/pharm_chemie/Arbeitskreise/AK_Stark

Fields of interest:

Medicinal chemistry, Lead identification and optimization; GPCR: biogenic amines, histamine, dopamine; Lipids: COX, 5-LO, Sphingolipids; Enzymes; Ion channels; Drug development

Recent publications:

M. Tomasch, J. S. Schwed, A. Paulke, H. Stark:
Bodilisant – A Novel Fluorescent, Highly Affine Histamine H3 Receptor Ligand,
ACS Med. Chem. Lett. Vol. 4, (2013), pp. 269-273.

A. Bahi, J. S. Schwed, M. Walter, H. Stark, B. Sadek:
Influence of the Novel Histamine H3 Receptor Antagonist ST1283 on Voluntary Alcohol Consumption and Ethanol-induced Place Preference in Mice,
Psychopharmacol. Vol. 228, (2013), pp. 85-95.

S. Schiffmann, D. Hartmann, S. Fuchs, K. Birod, N. Ferreiròs, Y. Schreiber, A. Zivkovic, G. Geisslinger, S. Grösch, H. Stark:
Inhibitors of Specific Ceramide Synthases,
Biochimie Vol. 94, (2012), pp. 558-565.

Hofmann, S. Barzen, C. B. Rödl, A. Kiehl, J. Borig, A. Zivkovic, H. Stark, G. Schneider, D. Steinhilber:
A Class of 5-Benzylidene-2-phenyl-thiazolinones with High Potency as Direct 5-Lipoxygenase Inhibitors,
J. Med. Chem. Vol. 54, (2011), pp. 1943-1947.

T. Kottke, K. Sander, L. Weizel, E. H. Schneider, R. Seifert, H. Stark:
Receptor-Specific Functional Efficacies of Alkyl Imidazoles as Dual Histamine H3/H4 Receptor Ligands,
Eur. J. Pharmacol. Vol. 654, (2011), pp. 200-208.