Geoffrey McFadden

Professor
School of Botany
University of Melbourne, Australia
E-mail: gim@unimelb.edu.au
Page: http://www.geoffmcfadden.com/McFadden_Lab/Home.html

Field of interests:

Molecular biology and biochemistry of Malaria

New drugs to fight Malaria

Endosymbiosis and the origin of plastids

Origin of apicomplexans

 

Recent publications:

Angrisano F, Tan YH, Sturm A, McFadden GI, Baum J:
Malaria parasite colonisation of the mosquito midgut – Placing the Plasmodium ookinete centre stage. 
Int J Parasitol., 2012 Mar 3. [Epub ahead of print] PubMed PMID: 22406332.   

Angrisano F, Riglar DT, Sturm A, Volz JC, Delves MJ, Zuccala ES, Turnbull L, Dekiwadia C, Olshina MA, Marapana DS, Wong W, Mollard V, Bradin CH, Tonkin CJ, Gunning PW, Ralph SA, Whitchurch CB, Sinden RE, Cowman AF, McFadden GI, Baum J:
Spatial Localisation of Actin Filaments across Developmental Stages of the Malaria Parasite. 
PLoS One, 7(2), (2012) :e32188.

van Dooren GG, Kennedy AT, McFadden GI:
The Use and Abuse of Heme in Apicomplexan Parasites. 
Antioxid Redox Signal., 2012 Mar 16. [Epub ahead of print] PubMed PMID: 22320355.   

Jackson KE, Pham JS, Kwek M, De Silva NS, Allen SM, Goodman CD, McFadden GI, de Pouplana LR, Ralph SA:
Dual targeting of aminoacyl-tRNA synthetases to the apicoplast and cytosol in Plasmodium falciparum. 
Int J Parasitol., 42(2), (2012): 177-186.

Angrisano F, Delves MJ, Sturm A, Mollard V, McFadden GI, Sinden RE, Baum J:
A  GFP-Actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle. 
Mol Biochem Parasitol., 182(1-2), (2012): 93-96.

Botté CY, Dubar F, McFadden GI, Maréchal E, Biot C:
Plasmodium falciparum Apicoplast Drugs: Targets or Off-Targets? 
Chem Rev., 112(3), (2012): 1269-1283.

Botté CY, Yamaryo-Botté Y, Janouskovec J, Rupasinghe T, Keeling PJ, Crellin P, Coppel RL, Maréchal E, McConville MJ, McFadden GI:
Identification of plant-like galactolipids in Chromera velia, a photosynthetic relative of malaria parasites.
J Biol Chem., 286(34), 2011: 29893-29903.

Johnson RA, McFadden GI, Goodman CD:
Characterization of two malaria parasite  organelle translation elongation factor G proteins: the likely targets of the anti-malarial fusidic acid.
PLoS One, 6(6), (2011): e20633.

Nair SC, Brooks CF, Goodman CD, Strurm A, McFadden GI, Sundriyal S, Anglin JL, Song Y, Moreno SN, Striepen B:
Apicoplast isoprenoid precursor synthesis and the  molecular basis of fosmidomycin resistance in Toxoplasma gondii. 
J Exp Med., 208(7), (2011): 1547-1559.

McFadden GI:
The apicoplast. 
Protoplasma, 248(4), (2011): 641-650.