Mohamed Lamkanfi

Group Leader
Department of Medical Protein Research
VIB and Ghent University

Fields of interest

To gain insight into the role of NLRs and inflammasomes in human disease.


Recent publications

Anand P, Malireddi R, Lukens J, Vogel P, Bertin J, Lamkanfi M, Kanneganti T.
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens.
NATURE, 488, 389-93, 2012

Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour L, Lamkanfi M, Louie S, Kayagaki N, Liu J, Kömüves L, Cupp J, Arnott D, Monack D, Dixit V.
Phosphorylation of NLRC4 is critical for inflammasome activation.
NATURE, 490, 539-42, 2012

Lamkanfi M, Dixit V.
Inflammasomes and their roles in health and disease.
Annual Review of Cell and Developmental Biology, 28, 137-61, 2012

Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee W, Roose-Girma M, Dixit V.
Non-canonical inflammasome activation targets caspase-11.
NATURE, 479, 117-21, 2011

Lamkanfi M.
Emerging inflammasome effector mechanisms.