Darren J. Obbard

Research Fellow
Institute of Evolutionary Biology
University of Edinburgh
E-mail: Darren.obbard@ed.ac.uk
Page: http://www.biology.ed.ac.uk/research/groups/obbard/

Fields of interest: 

Evolutionary genetics/genomics of Insect-pathogen interaction


Recent publications:

Obbard DJ, Jiggins FM, Bradshaw NJ, Little TJ:
Recent and recurrent selective sweeps of the antiviral RNAi gene Argonaute-2 in three species of Drosophila.
Molecular Biology and Evolution, 28(2), (2011): 1043-1056.

Longdon B, Hadfield JD, Webster CL, Obbard DJ, Jiggins FM:
Host phylogeny determines viral persistence and replication in novel hosts.
PLoS Pathogens 7(9), (2011): e1002260.

Longdon B, Wilfert L, Osei-Poku J, Cagney H, Obbard DJ, Jiggins FM:
Host-switching by a vertically transmitted rhabdovirus in Drosophila.
Biology Letters 7(5), (2011): 747-750.

Longdon B, Wilfert L, Obbard DJ, Jiggins FM:
Rhabdoviruses in two species of Drosophila: vertical transmission and a recent sweep.
Genetics, 188(1), (2011): 141-150.

Longdon B, Obbard DJ, Jiggins FM:
Sigma viruses from three species of Drosophila form a major new clade in the rhabdovirus phylogeny.
Proceedings of the Royal Society B, 277, (2010): 35-44.

Obbard DJ, Welch JJ, Little TJ:
Inferring selection in the Anopheles gambiae species complex: an example from immune-related serine protease inhibitors.
Malaria Journal, 8, (2009): 117.

Obbard DJ, Callister D, Jiggins FM, Soares D, Yan G, Little TJ:
The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae.
BMC Evolutionary Biology, 8, (2008): 174.

Obbard DJ, Welch JJ, Kim K-W, Jiggins FM:
Quantifying Adaptive Evolution in the Drosophila Immune System.
PLoS Genetics, 5(10), (2009): e1000698.

Obbard DJ, Gordon KHJ, Buck AH, Jiggins FM:
The evolution of RNAi as a defence against viruses and transposable elements.
Philosophical Transactions of the Royal Society Series B, 364, (2009): 99-115.

Obbard DJ, Jiggins FM, Halligan DL, Little TJ:
Natural selection drives extremely rapid evolution in antiviral RNAi genes.
Current Biology 16, (2006): 580-585.