Vladimir Parpura

Associate Professor of Neuroscience
Department of Neurobiology
University of Alabama, Birmingham, USA
E-mail: vlad@uab.edu
Page: http://neurobiology-uab.infomedia.com/bios.asp?action=form&recordID=209600

Fields of interest:

Calcium-dependent glutamate release from astrocytes, visualization of vesicular/receptor trafficking,  interactions between exocytotic proteins using single molecule detection approaches, development of scaffolds and dispersible materials, most notably modified carbon nanotubes, bio-mimetic micro-robotics

 

Recent publications:

Verkhratsky A, Parpura V, Rodríguez JJ (2011):
Where the thoughts dwell: The physiology of neuronal-glial “diffuse neural net”
Brain Res Rev 66: 133-151.

Reyes RC, Perry G, Lesort M, Parpura V (2011):
Immunophilin Deficiency Augments Ca2+- Dependent Glutamate Release from Mouse Cortical Astrocytes.
Cell Calcium 49: 21-34.

Losón OC, Ha CH, Parpura V (2011):
Age-dependent spatial segregation of synaptobrevin 2- containing vesicles in astrocytes.
J Neurochem 116:909-915.

Parpura  V, Grubisic V, Verkhratsky A (2011):
Ca2+ sources for the exocytotic release of glutamate from astrocytes.
Biochim Biophys Acta 1813: 984-991.

Lalo U, Pankratov Y, Parpura V, Verkhratsky A (2011):
Ionotropic receptors in neuronalastroglial signalling: What is the role of “excitable” molecules in non-excitable cells.
Biochim Biophys Acta1813: 992-1002.

Kapoor N, Lee W, Clark E, Bartoszewski R, McNicholas CM, Latham CB, Bebok Z, Parpura V, Fuller CM, Palmer CA, Benos DJ (2011):
Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes.
Am J Physiol Cell Physiol  300:C1246-C1259.

Jorgačevski J, Potokar M, Grilc S, Kreft M, Liu W, Barclay JW, Bückers J, Medda R, Hell SW, Parpura V, Burgoyne RD, Zorec R (2011):
Munc18-1 tuning of vesicle merger and fusion pore properties.
J Neurosci 31: 9055–9066.

Stout RF Jr, Parpura V (2011):
Voltage-gated calcium channel types in cultured C. elegans CEPsh glial cells.
Cell Calcium 50: 98-108.

Malarkey EB, Parpura V (2011):
Temporal characteristics of vesicular fusion in astrocytes: Examination of synaptobrevin 2 laden vesicles at single vesicle resolution.
J Physiol  589: 4271-4300.

Liu W, Montana V, Parpura V, Mohideen U (2011):
Single molecule measurements of dissociation rates and energy landscapes of binary trans SNARE complexes in parallel versus antiparallel orientation.
Biophys J, 101: 1864-1862.