Alexander S. Raikhel

Distinguished Professor
University of California Riverside

Fields of interest: 

Insect immunity, small RNAs, mosquito-pathogen interaction


Recent publications:

Pan X, Zhou G, Wu J, Bian G, Lu P, Raikhel AS, Xi Z:
Wolbachia induces ROS-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti.
Proc. Natl. Acad. Sci. USA, 109, (2012): E23-E31.

Shin SW, Zou Z, Raikhel AS:
A new player in the Aedes aegypti immune response: CLSP2 modulates melanization.
EMBO Reports 12, (2011): 938-943.

Zou Z, Souza-Neto JA, Xi Z, Kokoza V, Shin SW, Dimopoulos G, Raikhel AS:
Transcriptome analysis of Aedes aegypti transgenic mosquitoes with altered immunity.
Plos Pathog. 7, (2011): 11. e1002394.

Kokoza V, Ahmed A, Shin SW, Okafor N, Zou Z, Raikhel AS:
Blocking of Plasmodium transmission by cooperative action of Cecropin A and Defensin A in transgenic Aedes aegypti mosquitoes.
Proc. Natl. Acad. Sci. USA 107, (2010): 8111-8116.

Zou Z, Shin SW, Alvarez KS, Kokoza K, Raikhel AS:
Distinct melanization mechanisms in the mosquito Aedes aegypti.
Immunity 32, (2010): 41-53.

Bartholomay al:
Pathogenomics of Culex quinquefasciatus and Meta-Analysis of Infection Responses to Diverse Pathogens.
Science, 330, (2010): 88–90.

Zou Z, Shin SW, Alvarez KS, Bian G, Kokoza K, Raikhel AS:
Mosquito RUNX4 in the immune regulation of PPO gene expression and its effect on avian malaria parasite infection.
Proc. Natl. Acad. Sci. USA, 105, (2008): 18454-18459.

Waterhouse RM, et al:
Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.
Science, 316, (2007): 1738-1743.

Shin SW, Bian G, Raikhel AS:
A toll receptor and a cytokine, Toll5A and Spz1C, are involved in toll antifungal immune signaling in the mosquito Aedes aegypti.
J Biol Chem., 281, (2006): 39388-39395.

Bian G, Shin SW, Cheon HM, Kokoza V, Raikhel AS:
Transgenic alteration of Toll immune pathway in the female mosquito Aedes aegypti.
Proc. Natl. Acad. USA 102, (2005): 13568-13573.