Rona Ramsay

Reader in Biochemistry
Biomolecular Sciences Building
University of St Andrews, Fife, UK

Fields of interest:

Molecular enzymology (particularly membrane bound mitochondrial enzymes MAO A, MAO B and carnitine acyltransferases)


Recent publications:

Ramsay RR, Olivieri A, Holt A.:
An improved approach to steady-state analysis of monoamine oxidases.
J Neural Transm., 2011, 118: 2164-3793.

Dixon Clarke SE, Ramsay RR.:
Dietary inhibitors of monoamine oxidase A.
J Neural Transm., 2011, 118: 2119-0052

McDonald GR, Olivieri A, Ramsay RR, Holt A.:
On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B.
Pharmacol. Res.,2010, 62: 2083-2472.

Lühr S, Vilches-Herrera M, Fierro A, Ramsay RR, Edmondson DE, Reyes-Parada M, Cassels BK, Iturriaga-Vásquez P.:
2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.
Bioorg. Med. Chem., 2010, 18: 2012-3154.

Zammit VA, Ramsay RR, Bonomini M, Arduini A.:
Carnitine, mitochondrial function and therapy.
Adv. Drug Deliv. Rev., 2009, 61: 1971-6391.

Desino KE, Pignatello R, Guccione S, Basile L, Ansar S, Michaelis ML, Ramsay RR, Audus KL.:
TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability.
Biochem. Pharmacol., 2009, 78: 1967-9106.

Kay CW, El Mkami H, Molla G, Pollegioni L, Ramsay RR.:
Characterization of the covalently bound anionic flavin radical in monoamine oxidase a by electron paramagnetic resonance.
J Am. Chem. Soc., 2007, 129: 1804-4898.

Jones TZ, Giurato L, Guccione S, Ramsay RR.:
Interactions of imidazoline ligands with the active site of purified monoamine oxidase A.
FEBS J., 2007, 274: 1748-0205.

Ramsay RR, Jones TZ, Hynson RM.:
Alteration in spectral properties on ligand binding reveals flexibility in monoamine oxidase.
Med. Sci. Monit., 2005, 11: 1612-7378.

Jones TZ, Fleming P, Eyermann CJ, Gravestock MB, Ramsay RR.:
Orientation of oxazolidinones in the active site of monoamine oxidase.
Biochem. Pharmacol., 2005, 70: 1595-0194.