Andrew J. Roger

Department of Biochemistry and Molecular Biology
Dalhousie University, Canada

Field of interests:

Deep phylogeny of eukaryotes

Evolution of mitochondria-related organelles

Diversity and evolution of anaerobic metabolisms

Lateral gene transfer

Bioinformatic tools for molecular evolution

Modelling of protein sequence evolution


Recent publications:

Takishita K, Chikaraishi Y, Leger ML, Kim E, Yabuki A, Ohkouchi N, Roger AJ:
Lateral transfer of tetrahymenol-synthesizing genes has allowed multiple diverse eukaryote lineages to independently adapt to environments without oxygen.
Biology Direct, 7, (2012): 5.

Gaston D, Susko E, Roger AJ:
A phylogenetic mixture model for the identification of functionally divergent protein residues.
Bioinformatics, 27, (2011): 2655-2663.

Hampl V, Stairs CW, Roger AJ:
The tangled past of eukaryotic enzymes involved in anaerobic metabolism.
Mobile Genet. Elements, 3, (2011): 71-74.

Kamikawa R, Inagaki Y, Roger AJ, Hashimoto T:
Splintrons in Giardia intestinalis: Spliceosomal introns in a split form.
Commun. Integr. Biol., 4, (2011): 454-456.

Long S, Changmai P, Tsaousis AD, Skalický T, Verner Z, Wen YZ, Roger AJ, Lukeš J:
Stage-specific requirement for Isa1 and Isa2 proteins in the mitochondrion of Trypanosoma brucei and heterologous rescue by human and Blastocystis orthologues.
Mol. Microbiol., 81, (2011): 1403-1418.

Stairs CW, Roger AJ, Hampl V:
Eukaryotic pyruvate formate lyase and its activating enzyme were acquired laterally from a firmicute.
Mol. Biol. Evol., 28, (2011): 2087-2099.

Zou L, Susko E, Field C, Roger AJ:
The Parameters of the Barry and Hartigan general Markov model are statistically nonidentifiable.
Syst. Biol., 60, (2011): 872-875.

Wang H-C, Susko E, Roger AJ:
Fast statistical tests for detecting heterotachy in protein evolution.
Mol. Biol. Evol., 28, (2011): 2305-2315.

Kamikawa R, Inagaki Y, Tokoro M, Roger AJ, Hashimoto T:
Split introns in the genome of a divergent eukaryote Giardia intestinalis are excised by spliceosome-mediated trans-splicing.
Current Biol., 21, (2011): 311-315.

Tsaousis AD, Gaston D, Stechmann A, Walker PB, Lithgow T, Roger AJ:
A functional Tom70 in the human parasite Blastocystis sp.: Implications for the evolution of the mitochondrial import apparatus.
Mol. Biol. Evol., 28, (2011): 781-791.