Julien Royet

Principal investigator, Head of the Development and Immunology Master Program
Institut de Biologie du Développement de Marseille Luminy
E-mail: julien.royet@univmed.fr
Page: http://www.ibdml.univ-mrs.fr/equipes/equipe.php?id=63

Fields of interest: 

Genetic dissection of Drosophila immune mechanisms


Recent publications:

Akhouayri I, Turc C, Royet J, Charroux B:
Toll-8/Tollo Negatively Regulates Antimicrobial Response in the Drosophila Respiratory Epithelium.
PLoS Pathog 7(10), (2011): e1002319.

Royet J, Gupta D, Dziarski R:
Peptidoglycan recognition proteins: modulators of the microbiome and inflammation.
Nat Rev Immunol., 11(12, (2011): 837-851.

Storelli G, Defaye A, Erkosar B, Hols P, Royet J, Leulier F:
Lactobacillus plantarum romotes Drosophila systemic growth by modulating hormonal signals through TOR dependent nutrient sensing.
Cell Metabolism. 14(3), (2011): 403-415.

Rival T, Macchi M, Arnauné-Pelloquin L, Poidevin M, Maillet F, Richard F, Fatmi A, Belenguer P, Royet J:
Inner-membrane proteins PMI/TMEMM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.
EMBO Rep.,12(3), (2011): 223-230.

Charroux B, Royet J:
Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response.
Proc Natl Acad Sci U S A.,106(24), (2009): 9797-9802.

Maillet F, Bischoff V, Vignal C,, Hoffmann J, Royet J:
The Drosophila membrane-associated protein PGRP-LF prevents IMD/JNK pathways triggering by blocking PGRP-LC activation.
Cell Host and Microbe, 2, (2008): 17-28.

Bischoff V, Vignal C, B.Duvic Boneca I, Hoffmann JA, Royet J:
Downregulation of theDrosophila Immune Response by Peptidoglycan Recognition Proteins SC1 and SC2.
PLoS Pathogen., 2(2), (2006): e14.

Bischoff V, Vignal C, Boneca I, Michel T, Hoffmann JA, Royet J:
Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria.
Nat. Immunol., 5, (2004): 1175-1180.

Gottar M, Gobert V, Michel T, Belvin M, Duyk G, Hoffmann JA, Ferrandon D, Royet J:
The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein.
Nature, 416, (2002): 640-644.

Michel T, Reichhart JM, Hoffmann JA, Royet J:
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein.
Nature, 414, (2001): 756-759.