Bart B. P. Rutten M.D., Ph.D.

assistant professor, vice-coordinator EU-GEI,
Maastricht University Medical Centre, School for Mental Health and Neuroscience

Fields of interest:

gene-environment interactions, epigenetics, mental health, resilience, schizophrenia, depression, aging and Alzheimer’s disease


Recent publications:

Schmidt-Kastner R., van Os J., Esquivel G., Steinbusch H. W., Rutten B. P.:
An environmental analysis of genes associated with schizophrenia: hypoxia and vascular factors as interacting elements in the neurodevelopmental model,
Mol. Psychiatry, 2012, doi: 10.1038/mp.2011.183

Chouliaras L., van den Hove D. L., Kenis G., Keitel S., Hof P. R., van Os J., Steinbusch H. W., Schmitz C., Rutten B. P.:
Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction,
Neurobiol. Aging, 2011, [Epub ahead of print]

Peerbooms O. L., van Os J., Drukker M, Kenis G., Hoogveld L.:
Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability?,
Brain Behav. Immun., 2011, 25, 1530-1543

Chouliaras L., van den Hove D. L., Kenis G., Dela Cruz J., Lemmens M. A., van Os J., Steinbusch H. W., Schmitz C., Rutten B. P.:
Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus,
Brain Behav. Immun., 2011, 25, 616-623

Van Os J., Kenis G., Rutten B. P.:
The environment and schizophrenia,
Nature, 2010, 468, 203-212.

Chouliaras L., Sierksma A. S., Kenis G., Prickaerts J., Lemmens M. A., Brasnjevic I., van Donkelaar E. L., Martinez-Martinez P., Losen M., De Baets M. H., Kholod N., van Leeuwen F., Hof P. R., van Os J., Steinbusch H. W., van den Hove D. L., Rutten B. P.:
Gene-environment interaction research and transgenic mouse models of Alzheimer’s disease,
Int. J. Alzheimers Dis., 2010, pii: 859101

Rutten B. P., Brasnjevic I., Steinbusch H. W., Schmitz C:
Caloric restriction and aging but not overexpression of SOD1 affect hippocampal volumes in mice,
Mech. Ageing Dev., 2010, 131, 574-579

Peerbooms O. L., Wichers M., Jacobs N., Kenis G., Derom C., Vlietinck R., Thiery E., van Os J., Rutten B. P.:
No major role for X-inactivation in variations of intelligence and behavioral problems at middle childhood,
Am. J. Med. Genet. B Neuropsychiatr. Genet., 2010, 153B, 1311-1317

Rutten B. P., Mill J.:
Epigenetic mediation of environmental influences in major psychotic disorders,
Schizophr. Bull., 2009, 35, 1045-1056

Van Os J., Rutten B. P.:
Gene-environment-wide interaction studies in psychiatry,
Am. J. Psychiatry, 2009, 166, 964-966