Rohan de Silva

Reader in Neuroscience
Reta Lila Weston Institute
UCL Institute of Neurology
E-mail: rsilva@ion.ucl.ac.uk
Page: http:///www.ucl.ac.uk/rlweston-inst/Rohan-Bio.html

Fields of interest

  • Genetics and cell biology of neurodegeneration
  • Experimental neuropathology of tauopathies

Recent publications

Luk C, Vandrovcova J, Malzer E, Lees AJ, de Silva R:
Brain Tau Isoform mRNA and Protein Correlation in PSP Brain,
Translat. Neurosci. 2010; 1:30-36

Rohrer JD, Guerreiro R, Vandrovcova J, Uphill J, Reiman D, Beck J, Isaacs AM, Authier A, Ferrari R, Fox NC, Mackenzie IRA, Warren JD, de Silva R, Holton J, Revesz T, Hardy J, Mead S, Rossor MN:
The heritability and genetics of frontotemporal lobar degeneration, Mackenzie IRA, Warren JD, de Silva R, Holton J, Revesz T, Hardy J, Mead S,
Rossor MNNeurology 2009; 73:1451-1456

Vandrovcova J, Pittman AM, Malzer E, Abou-Sleiman PM, Lees AJ, Wood NW, de Silva R:
Association of MAPT haplotype-tagging SNPs with sporadic Parkinson's disease.
Neurobiol. Aging 2009; 30:1477-1482

Lace G, Savva GM, Forster G, de Silva R, Brayne C, Matthews FE, Barclay JJ, Dakin L, Ince PG, Wharton SB:
Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study,
Brain 2009; 132:1324-1334.

Luk C, Giovannoni G, Williams DR, Lees AJ, de Silva R:
Development of a sensitive ELISA for quantification of three- and four-repeat tau isoforms in tauopathies,
J. Neurosci. Meth. 2009; 180:34-42.

Silveira-Moriyama L, Sirisena D, Gamage P, Gamage R, de Silva R, Lees AJ:
Adapting the Sniffin' Sticks to diagnose Parkinson's disease in Sri Lanka,
Movement Disord. 2009; 24:1229-1233.

Momeni P, Pittman A, Lashley T, Vandrovcova J, Malzer E, Luk C, Hulette C, Lees A, Revesz T, Hardy J.:

Clinical and pathological features of an Alzheimer's disease patient with the MAPT DeltaK280 mutation,
de Silva R Neurobiol. Aging 2009; 30:388-393

Dickey C, Kraft C, Jinwal U, Koren J, Johnson A, Anderson L, Lutz L, Lee D, Dickson D, de Silva R, Binder LI, Davies P, Morgan D, Lewis J.:
Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.
Binder LI, Davies P, Morgan D, Lewis J Am. J. Pathol. 2009; 174: 228-238

Lashley T, Revesz T, Plant G, Bandopadhyay R, Lees AJ, Frangione B, Wood NW, de Silva R, Ghiso J, Rostagno A, Holton, JL.:
Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease,
Holton JL Neuropathol. Appl. Neurobiol. 2008; 34: 492-505

Kovacs GG, Pittman A, Revesz T, Luk C, Lees A, Kiss E, Tariska P, Laszlo L, Molnár K, Molnar MJ, Tolnay M, de Silva R:
MAPT S305I mutation: implications for argyrophilic grain disease.
Tolnay M, de Silva R Acta Neuropathol. 2008; 116:103-118