James C. Vickers

Professor of Pathology, PhD
NeuroRepair Group, Menzies Research Institute
University of Tasmania
E-mail: james.vickers@utas.edu.au
Page: http://fcms.its.utas.edu.au/healthsci/medicine/pagedetails.asp?lpersonId=1058


Fields of interest:

Cellular basis of the degeneration and regeneration of the nervous system

Alzheimer's disease, Parkinson's disease, motor neuron disease, glaucoma and brain trauma



Recent publications:

Chung R. S., Howells C., Eaton E. D., Shabala L., Zovo K., Palumaa P., Sillard R., Woodhouse A., Bennett W. R., Ray S., Vickers J. C., West A. K.:

The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons

PLoS One 2010; 5(8): e12030.


Mitew S., Kirkcaldie M. T., Halliday G. M., Shepherd C. E., Vickers J. C., Dickson T. C.:

Focal demyelination in Alzheimer's disease and transgenic mouse models

Acta Neuropathol. 2010; 119(5): 567-577.


Staal J. A., Dickson T. C., Gasperini R., Liu Y., Foa L., Vickers J. C.:

Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury

J. Neurochem. 2010; 112(5): 1147-1155.


Blizzard C. A., King A. E., Haas M. A., O'Toole D. A., Vickers J. C., Dickson T. C.:

Axonal shearing in mature cortical neurons induces attempted regeneration and the reestablishment of neurite polarity

Brain Res. 2009; 1300: 24-36.


Vickers J. C., King A. E., Woodhouse A., Kirkcaldie M. T., Staal J. A., McCormack G. H., Blizzard C. A., Musgrove R. E., Mitew S., Liu Y., Chuckowree J. A., Bibari O., Dickson T. C.:

Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system

Brain Res. Bull. 2009; 80(4-5): 217-223.


Woodhouse A., Vickers J. C., Adlard P. A., Dickson T. C.:

Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging

Neurobiol. Aging 2009; 30(6): 864-874.


Staal J. A., Dickson T. C., Chung R. S., Vickers J. C.:

Disruption of the ubiquitin proteasome system following axonal stretch injury accelerates progression to secondary axotomy

J. Neurotrauma 2009; 26(5): 781-788.


Woodhouse A., Shepherd C. E., Sokolova A., Carroll V. L., King A. E., Halliday G. M., Dickson T. C., Vickers J. C.:

Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease

Acta Neuropathol. 2009; 117(1): 19-29.


Robinson A. L., Emden C. G., Elder J. A., Lea E. J., Vickers J. C., Turner P. A.:

Multiple views reveal the complexity of dementia diagnosis

Australas. J. Ageing 2008; 27(4): 183-188.


Chung R. S., Penkowa M., Dittmann J., King C. E., Bartlett C., Asmussen J. W., Hidalgo J., Carrasco J., Leung Y. K., Walker A. K., Fung S. J., Dunlop S. A., Fitzgerald M., Beazley L. D., Chuah M. I., Vickers J. C., West A. K.:

Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury

J. Biol. Chem. 2008; 283(22): 15349-15358.